Article

A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. Implications for presymptomatic testing and screening

1995-02-15

Abstract excerpt

<h3>Objectives.</h3> —To report the initial experience of an international group of investigators in identifying mutations in the<i>BRCA1</i>breast and ovarian cancer susceptibility gene, to assess the spectrum of such mutations in samples from patients with different family histories of cancer, and to determine the frequency of recurrent mutations. <h3>Design.</h3> —Nine laboratories in North America and the Unit...

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Literature Corpus work: 85343e79-7879-5162-8cfe-1f57ab0d7d9f
DOI: 10.1001/jama.273.7.535

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