Article
Germline BRCA1 alterations in a population-based series of ovarian cancer cases.
Human molecular genetics - 1 May 1999
Janezic S A, Ziogas A, Krumroy L M, Krasner M, Plummer S J, Cohen P, Gildea M, Barker D, Haile R, Casey G, Anton-Culver H
Abstract excerpt
The objective of this study was to provide more accurate frequency estimates of breast cancer susceptibility gene 1 ( BRCA1 ) germline alterations in the ovarian cancer population. To achieve this, we determined the prevalence of BRCA1 alterations in a population-based series of consecutive ovarian cancer cases. This is the first population-based ovarian cancer study reporting BRCA1 alterations derived from a...
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