Article
Recurrent TP53 missense mutation in cancer patients of Arab descent.
Familial cancer - 1 Apr 2017
Zick Aviad, Kadouri Luna, Cohen Sherri, Frohlinger Michael, Hamburger Tamar, Zvi Naama, Plaser Morasha, Avital Eilat, Breuier Shani, Elian Firase, Salah Azzam, Goldberg Yael, Peretz Tamar
Abstract excerpt
Hereditary cancer comprises more than 10% of all breast cancer cases. Identification of germinal mutations enables the initiation of a preventive program that can include early detection or preventive treatment and may also have a major impact on cancer therapy. Several recurrent mutations were identified in the BRCA1/2 genes in Jewish populations however, in other ethnic groups in Israel, no recurrent mutations...
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