Article
BRCA1 sequence variations in 160 individuals referred to a breast/ovarian family cancer clinic. Institut Curie Breast Cancer Group.
American journal of human genetics - 1 May 1997
Stoppa-Lyonnet D, Laurent-Puig P, Essioux L, Pagès S, Ithier G, Ligot L, Fourquet A, Salmon R J, Clough K B, Pouillart P, Bonaïti-Pellié C, Thomas G
Abstract excerpt
An account of familial aggregation in breast/ovarian cancer has become possible with the identification of BRCA1 germ-line mutations. We evaluated, for 249 individuals registered with the Institut Curie in Paris, the prior probability that an individual carried a mutation that predisposes to thes...
Topics
- Africa
- Breast Neoplasms
- Cancer Care Facilities
- Causality
- Codon, Nonsense
- Europe
- Family Practice
- Female
- Frameshift Mutation
- France
- Genes, BRCA1
- Genetic Testing
- Genetic Variation
- Humans