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Article

Five recurrent BRCA1/2 mutations are responsible for cancer predisposition in the majority of Slovenian breast cancer families.

BMC medical genetics - 10 Sept 2008

Krajc Mateja, Teugels Erik, Zgajnar Janez, Goelen Guido, Besic Nikola, Novakovic Srdjan, Hocevar Marko, De Grève Jacques

Abstract excerpt

BACKGROUND: Both recurrent and population specific mutations have been found in different areas of the world and more specifically in ethnically defined or isolated populations. The population of Slovenia has over several centuries undergone limited mixing with surrounding populations. The current study was aimed at establishing the mutation spectrum of BRCA1/2 in the Slovenian breast/ovarian cancer families...

Read the complete abstract on PubMed

Topics

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Share to Breast Neoplasms, Male
Share to Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA2

Share to Mutation, Missense

Share to Neoplastic Syndromes, Hereditary

Share to Ovarian Neoplasms

Share to Sequence Deletion

Share to Slovenia

Source

Open in PubMed Open full text

Identifiers

PMID: 18783588
DOI: 10.1186/1471-2350-9-83
PMCID: PMC2547096

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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