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Identifying Causal Relations between Gut Microbiome, Metabolic Dysfunction-Associated Fatty Liver Disease and the Novel Mediators of Blood Metabolites

2024-08-07

Abstract excerpt

<h4>Background</h4> Research has established connection between gut microbiome and the risk of metabolic dysfunction-associated fatty liver disease (MAFLD). However, the causal relationships and the roles of potential mediating factors, such as blood metabolites, remain unclear. <h4>Methods</h4> We conducted a bidirectional and mediation Mendelian randomization (MR) study using the genome-wide summary statistics...

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Literature Corpus work
852005ad-9262-5de3-883d-dbc52fa182e9
DOI
10.1101/2024.08.05.606637
Open publication

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