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Article

Metabolites mediate the causal associations between gut microbiota and NAFLD: a Mendelian randomization study

31 Jul 2024

Abstract excerpt

BACKGROUND: Although gut microbiota and serum metabolite composition have been observed to be altered in patients with non-alcoholic fatty liver disease (NAFLD), previous observational studies have demonstrated inconsistent results. As this may be influenced by factors such as confounders and reverse causality, we used Mendelian randomization to clarify the causal effect of gut microbiota and blood metabolites on...

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PMID: 39085775
DOI: 10.1186/s12876-024-03277-w

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