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Article

Causal relationships between the gut microbiome, blood lipids, and heart failure: a Mendelian randomization analysis.

European journal of preventive cardiology - 6 Sept 2023

Dai Huajie, Hou Tianzhichao, Wang Qi, Hou Yanan, Wang Tiange, Zheng Jie, Lin Hong, Zhao Zhiyun, Li Mian, Wang Shuangyuan, Zhang Di, Dai Meng, Zheng Ruizhi, Lu Jieli, Xu Yu, Chen Yuhong, Ning Guang, Wang Weiqing, Bi Yufang, Xu Min

Abstract excerpt

AIMS: Studies have linked gut microbiome and heart failure (HF). However, their causal relationships and potential mediating factors have not been well defined. To investigate the causal relationships between the gut microbiome and HF and the mediating effect of potential blood lipids by using genetics. METHODS AND RESULTS: We performed a bidirectional and mediation Mendelian randomization (MR) study using...

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PMID: 37195998
DOI: 10.1093/eurjpc/zwad171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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