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Article

Exploring causal effects of gut microbiota and metabolites on body fat percentage using two-sample Mendelian randomization.

Diabetes, obesity & metabolism - 1 Sept 2024

Wang Xiaojun, Lu Chunrong, Li Xiang, Ye Pengpeng, Ma Jie, Chen Xiaochun

Abstract excerpt

AIM: The relationship between the gut microbiota, metabolites and body fat percentage (BFP) remains unexplored. We systematically assessed the causal relationships between gut microbiota, metabolites and BFP using Mendelian randomization analysis. MATERIALS AND METHODS: Single nucleotide polymorphisms associated with gut microbiota, blood metabolites and BFP were screened via a genome-wide association study...

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PMID: 38828839
DOI: 10.1111/dom.15692

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