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Assessing the causal relationships between human blood metabolites and the risk of NAFLD: A comprehensive mendelian randomization study

28 Mar 2023

Abstract excerpt

Background: Non-alcoholic fatty liver disease (NAFLD) is a liver disease associated with obesity, insulin resistance, type 2 diabetes mellitus (T2DM), and metabolic syndrome. The risk factors for NAFLD have not been identified. Metabolic dysfunction has been found to be an important factor in the pathogenesis and progression of NAFLD. However, the causal impact of blood metabolites on NAFLD is unclear. Methods:...

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PMID: 37056283
DOI: 10.3389/fgene.2023.1108086

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