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Article

Genetic associations between gut microbiota and type 2 diabetes mediated by plasma metabolites: a Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Zheng XuWen, Chen MaoBing, Zhuang Yi, Zhao Liang, Qian YongJun, Xu Jin, Fan JinNuo

Abstract excerpt

Background: Numerous research studies have indicated a possible association between type 2 diabetes (T2DM) and gut microbiota. To explore specific metabolic pathways connecting gut microbiota and T2DM, we employed Mendelian randomization (MR) and linkage disequilibrium score regression (LDSC) techniques. Methods: This research utilized data from genome-wide association studies (GWAS) that are publicly accessible....

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Share to Diabetes Mellitus, Type 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39184139
DOI: 10.3389/fendo.2024.1430675
PMCID: PMC11341399

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