Article

Integrated Cross-Organ Transcriptomic Analysis Uncovers Conserved Gene Signatures Predictive of Allograft Rejection

2025-11-09

Abstract excerpt

Long-term transplant success is limited by allograft rejection, a complex process traditionally studied on an organ-specific basis. To establish a unified framework beyond organ-specific studies, we performed a network-based systems biology analysis of transcriptomic data from 672 liver, kidney, and heart transplant biopsies to identify a conserved, pan-organ molecular framework of rejection. By constructing and c...

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Literature Corpus work: 851fbee8-b501-55fb-beaa-e3a114d40a78
DOI: 10.1101/2025.11.07.687316

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Integrated Cross-Organ Transcriptomic Analysis Uncovers Conserved Gene Signatures Predictive of Allograft RejectionDOI 10.1101/2025.11.07.687316Read

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