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Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis

12 Oct 2011

Abstract excerpt

In humans, the role and relationship between molecular pathways that lead to tissue destruction during acute allograft rejection are not fully understood. Based on studies conducted in humans, we recently hypothesized that different immune-mediated tissue destruction processes (i.e. cancer, infection, autoimmunity) share common convergent final mechanisms. We called this phenomenon the "Immunologic Constant of...

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PMID: 21992116
DOI: 10.1186/1479-5876-9-174

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