Article

<i>Vegfr3</i> is required in the <i>Tbx1</i> expression domain for cardiac outflow tract development

2026-06-02

Abstract excerpt

Gene inactivation in model organisms has identified numerous genes and signaling pathways involved in mammalian cardiac OFT development. Human genetics data have implicated the VEGFR3 gene in OFT development but when and where it is required is unknown. In this study we determined the sensitivity of the developing murine cardiac OFT to reduced Vegfr3 gene dosage and we tested whether its’ requirement is dependen...

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Identifiers and source

Literature Corpus work: 85006d9c-852d-5895-86bd-2e27288cf8b8
DOI: 10.64898/2026.05.29.728669

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