Article

Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia

2023-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Fanconi anemia (FA) is a rare genetic disease characterized by heterogeneous congenital abnormalities and increased risk for bone marrow failure and cancer. FA is caused by mutation of any one of 23 genes, the protein products of which function primarily in the maintenance of genome stability. An important role for the FA proteins in the repair of DNA interstrand crosslinks (ICLs) has been estab...

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Literature Corpus work: 84f2bcdd-e53b-50e2-97d6-365df5041b4f
DOI: 10.1101/2023.04.06.535759

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