Article

Functional genomics guided multi-omics framework identifies aldehyde metabolism as a therapeutic vulnerability in Fanconi anaemia

2026-08-26

Abstract excerpt

Understanding the molecular vulnerabilities associated with Fanconi anemia (FA) is essential for identifying therapeutic opportunities and elucidating the mechanisms underlying disease progression and cancer predisposition. However, progress in this area remains constrained by limited availability of representative FA cellular models. To address this challenge, we defined an FA-like cellular state by identifying c...

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Literature Corpus work: d7621e7a-70bc-5c73-9e21-dc8c04c5d1c7
DOI: 10.64898/2026.08.26.747186

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