Article

C. elegans Nuclear Hormone Receptor NHR-49 promotes attractive chemotaxis independently of its role in fatty acid metabolism

2026-08-24

Abstract excerpt

All organisms must sense and adapt to environmental cues to survive and thrive. In the nematode worm Caenorhabditis elegans, the nuclear hormone receptor nhr-49 is required for lipid homeostasis, stress resilience, pathogen defense, and longevity. In addition, recent studies suggest that NHR-49 controls avoidance behaviors and aversive memory to pathogenic bacteria and mitochondrial disruption, acting via its esta...

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Literature Corpus work: 8489f98c-0756-5174-8a83-6180908b5f7e
DOI: 10.64898/2026.08.19.745339

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