Article
Transcriptional profiling reveals differential expression of a neuropeptide-like protein and pseudogenes in aryl hydrocarbon receptor-1 mutant Caenorhabditis elegans.
Comparative biochemistry and physiology. Part D, Genomics & proteomics - 1 Mar 2014
Aarnio Vuokko, Heikkinen Liisa, Peltonen Juhani, Goldsteins Gundars, Lakso Merja, Wong Garry
Abstract excerpt
The aryl hydrocarbon receptor (AHR) functions in higher organisms in development, metabolism and toxic responses. Its Caenorhabditis elegans (C. elegans) ortholog, AHR-1, facilitates neuronal development, growth and movement. We investigated the effect of AHR mutation on the transcriptional profile of L4 stage C. elegans using RNA-seq and quantitative real time PCR in order to understand better AHR-1 function at...
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