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Nuclear hormone receptor NHR-49 shapes immuno-metabolic response of <i>Caenorhabditis elegans to Enterococcus faecalis</i> infection

2019-02-14

Abstract excerpt

<h4>ABSTRACT</h4> Immune responses to pathogenic microbes include activation of resistance and tolerance mechanisms in the host both of which are energetically expensive. In this study, we show that C. elegans exposed to Gram positive bacteria Enterococcus faecalis and Staphylococcus aureus , rapidly utilizes lipid droplets, the major energy reserve in the nematode. Feeding on E. faecalis causes developmental...

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Literature Corpus work
a2509e47-9147-58a8-9722-9be6ef6bc81f
DOI
10.1101/549907
Open publication

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