Article

Decoding the Spatial and Epigenetic Logic of Early Skin Development

2025-09-19

Abstract excerpt

The embryonic epidermis originates from a simple single-layered ectoderm that undergoes precise transcriptional and morphological transitions to generate a self-replenishing, multi-layered epidermis. A key early milestone is the emergence of the periderm; a transient, protective layer whose disruption underlies a series of devastating human congenital disorders. Despite its importance, the gene regulatory networks...

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Literature Corpus work: 8464d0ad-033b-5829-a69f-3e35dbe7feb1
DOI: 10.1101/2025.09.19.677295

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