Article
Transcriptional and signalling regulation of skin epithelial stem cells in homeostasis, wounds and cancer
29 Nov 2020
Abstract excerpt
The epidermis and skin appendages are maintained by their resident epithelial stem cells, which undergo long-term self-renewal and multilineage differentiation. Upon injury, stem cells are activated to mediate re-epithelialization and restore tissue function. During this process, they often mount lineage plasticity and expand their fates in response to damage signals. Stem cell function is tightly controlled by...
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