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Article

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation

1 Jun 2015

Abstract excerpt

The transcription factor p63 plays a pivotal role in keratinocyte proliferation and differentiation in the epidermis. However, how p63 regulates epidermal genes during differentiation is not yet clear. Using epigenome profiling of differentiating human primary epidermal keratinocytes, we characterized a catalog of dynamically regulated genes and p63‐bound regulatory elements that are relevant for epithelial...

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PMID: 26034101
DOI: 10.15252/embr.201439941

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