Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional differences in airway dendritic cells determine susceptibility to IgE-sensitization.

Immunology and cell biology - 1 Mar 2018

Leffler Jonatan, Mincham Kyle T, Mok Danny, Blank Fabian, Holt Patrick G, Stumbles Philip A, Strickland Deborah H

Abstract excerpt

Respiratory IgE-sensitization to innocuous antigens increases the risk for developing diseases such as allergic asthma. Dendritic cells (DC) residing in the airways orchestrate the immune response following antigen exposure and their ability to sample and present antigens to naïve T cells in airway draining lymph nodes contributes to allergen-specific IgE-sensitization. In order to characterize inhaled antigen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dendritic Cells
Share to Hypersensitivity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunization

Share to Immunoglobulin E

Share to Lymph Nodes

Share to Ovalbumin

Share to Rats, Inbred BN

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 29363184
DOI: 10.1111/imcb.12005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional differences in airway dendritic cells determine susceptibility to IgE-sensitization.PMID 29363184Read ↗

Allergic airways disease develops after an increase in allergen capture and processing in the airway mucosa.Semantic proximity Read ↗

A combination TLR7/8 and RIG-I agonist adjuvant reverts asthmatic allergic sensitization and prevents aggravated influenza infection in OVA-sensitized miceSemantic proximity Read ↗

How experimental models have unlocked hidden mechanisms of hypersensitivity pneumonitis.Semantic proximity Read ↗

Allergy Risk Is Mediated by Dendritic Cells with Congenital Epigenetic ChangesSemantic proximity Read ↗

Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of risk for persistent airways hyper-responsiveness in experimental asthmaSemantic proximity Read ↗

Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation.Semantic proximity Read ↗

Comparison of asthma phenotypes in OVA-induced mice challenged via inhaled and intranasal routes.Semantic proximity Read ↗

Complement regulates inhalation tolerance at the dendritic cell/T cell interface.Semantic proximity Read ↗

The role of airway dendritic cell populations in regulation of T-cell responses to inhaled antigens: atopic asthma as a paradigm.Semantic proximity Read ↗

Genetic variation influences immune responses in sensitive rats following exposure to TiO2 nanoparticles.Semantic proximity Read ↗

NO2 inhalation induces maturation of pulmonary CD11c+ cells that promote antigenspecific CD4+ T cell polarization.Semantic proximity Read ↗

Susceptibility of mice genetically deficient in the surfactant protein (SP)-A or SP-D gene to pulmonary hypersensitivity induced by antigens and allergens of Aspergillus fumigatus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.