Article
Haemophilus influenzae infection drives IL-17-mediated neutrophilic allergic airways disease.
PLoS pathogens - 1 Oct 2011
Essilfie Ama-Tawiah, Simpson Jodie L, Horvat Jay C, Preston Julie A, Dunkley Margaret L, Foster Paul S, Gibson Peter G, Hansbro Philip M
Abstract excerpt
A subset of patients with stable asthma has prominent neutrophilic and reduced eosinophilic inflammation, which is associated with attenuated airways hyper-responsiveness (AHR). Haemophilus influenzae has been isolated from the airways of neutrophilic asthmatics; however, the nature of the association between infection and the development of neutrophilic asthma is not understood. Our aim was to investigate the...
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