Article
Comparison of asthma phenotypes using different sensitizing protocols in mice.
The Korean journal of internal medicine - 1 Jun 2005
Chang Yoon-Seok, Kim Yoon-Keun, Bahn Joon-Woo, Kim Sang-Heon, Park Heung-Woo, Kim Tae-Bum, Cho Sang-Heon, Min Kyung-Up, Kim You-Young
Abstract excerpt
BACKGROUND: Several methods have been reported to induce asthmatic reactions in mice but few studies have compared their efficiency. We evaluated the efficiency of the protocols frequently used in the literature. METHODS: BALB/c mice were sensitized to ovalbumin (OVA) by intraperitoneal injection; 1] Once a week for two weeks using OVA with alum (IPOA-2) or without (IPO-2), and provocation on days 28-30 by 1% OVA...
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