Article

Base Editing of Human Pluripotent Stem Cells for modeling Long QT syndrome

2021-10-08

Abstract excerpt

<title>Abstract</title> <p>Human pluripotent stem cells (hPSCs) have great potential for disease modeling, drug discovery, and regenerative medicine as they can differentiate into many different functional cell types via directed differentiation. However, the application of disease modeling is limited due to a time-consuming and labor-intensive process of introducing known pathogenic mutations into hPSCs. Base ed...

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Literature Corpus work: 8411e84d-e7a8-5794-adc3-a85bf04dab43
DOI: 10.21203/rs.3.rs-954667/v1

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