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Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies

29 Aug 2019

Abstract excerpt

Long-QT syndrome, a frequently fatal inherited arrhythmia syndrome caused by genetic variants (congenital) or drugs (acquired), affects 1 in 2000 people worldwide. Its sentinel event is often sudden cardiac death, which makes preclinical diagnosis by genetic testing potentially life-saving. Unfortunately, clinical experience with genetic testing has shown that it is difficult to correctly identify genetic...

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PMID: 31465267
DOI: 10.1161/circresaha.119.315209

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