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Article

Genomic Engineering of Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Cavanaugh Christopher, Hesson Jennifer, Mathieu Julie

Abstract excerpt

Recent advances in patient-derived induced Pluripotent Stem Cell (iPSC) generation, improvement of cardiomyocyte-directed differentiation protocols, and the availability of new genome editing techniques have opened up new avenues for disease modeling of cardiomyopathies. Patients with cardiomyopathies often harbor a single-base substitution believed to be linked to the disease phenotype. Somatic cells derived...

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PMID: 38038847
DOI: 10.1007/978-1-0716-3527-8_8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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