Article

TCR repertoire profiling revealed antigen-driven CD8+ T cell clonal groups shared in synovial fluid of patients with spondyloarthritis

2022-05-10

Abstract excerpt

<h4>ABSTRACT</h4> Spondyloarthritis (SpA) comprises a number of inflammatory rheumatic diseases with overlapping clinical manifestations. Strong association with several HLA-I alleles and T cell infiltration into an inflamed joint suggest involvement of T cells in SpA pathogenesis. In this study, we performed high-throughput T cell repertoire profiling of synovial fluid (SF) and peripheral blood (PB) samples colle...

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Literature Corpus work: 83f53fa3-39a5-55f0-bb32-60b488442b52
DOI: 10.1101/2022.05.06.22274633

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