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AxSpA joint tissue is characterised by HLA-DR <sup>+</sup> tissue resident memory (TRM) and killer cell immunoglobulin-like receptor (KIR) <sup>+</sup> CD8 <sup>+</sup> T cell subsets

2024-10-14

Abstract excerpt

<h4>Objective</h4> Axial Spondyloarthritis (AxSpA) is a common inflammatory arthritis with HLA-B*27 as the major genetic risk. Recent discoveries of AxSpA-specific T cell receptor (TCR) motifs and the self and bacterial peptides that they recognize support a pathogenic role of CD8 + T cells. Despite of previous work on synovial fluid, the characteristics of CD8 cells in joint tissue are currently unknown. <h4>...

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Literature Corpus work
79e9910c-1516-5feb-8a31-41dc98e980d5
DOI
10.1101/2024.10.09.617402
Open publication

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AxSpA joint tissue is characterised by HLA-DR <sup>+</sup> tissue resident memory (TRM) and killer cell immunoglobulin-like receptor (KIR) <sup>+</sup> CD8 <sup>+</sup> T cell subsetsDOI 10.1101/2024.10.09.617402
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