Article

ZIP13/SLC39A13 integrates intracellular iron distribution with adipose energy metabolism

2026-06-02

Abstract excerpt

<title>Abstract</title> <p>Fine-tuning of lipid metabolism in adipose tissue is crucial for maintaining energy homeostasis and metabolic health. Beyond total metal abundance, the intracellular distribution of metal ions represents a fundamental yet largely unexplored regulatory layer of cellular metabolism. Here, we demonstrate that ZIP13/SLC39A13, originally identified as an intracellular zinc transporter, regul...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 83d5dcae-f9d6-53d3-9190-73e05254d526
DOI: 10.21203/rs.3.rs-3991001/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ZIP13/SLC39A13 integrates intracellular iron distribution with adipose energy metabolismDOI 10.21203/rs.3.rs-3991001/v1Read

Comparative Roles of ZIP and ZnT Zinc Transporters in Metabolic InflammationSemantic proximity Read

Recent Advances in the Role of SLC39A/ZIP Zinc Transporters In VivoSemantic proximity Read

Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expressionSemantic proximity Read

Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolismSemantic proximity Read

Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settingsSemantic proximity Read

Nutrigenomic profiling identifies ZIP10 (SLC39A10) as a regulator of erythroid zinc homeostasis with genetic associations to anemia risk.Semantic proximity Read

A Spatiotemporal Proteomic Map of Human AdipogenesisSemantic proximity Read

Zinc and its transporters, pancreatic β-cells, and insulin metabolism.Semantic proximity Read

Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome.Semantic proximity Read

Cytoplasmic zinc regulates IL-1β production by monocytes/macrophages via mTORC1-induced glycolysis in rheumatoid arthritis (RA)Semantic proximity Read

Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cellsSemantic proximity Read

ZIP transporters‐regulated Zn 2+ homeostasis: A novel determinant of human diseasesSemantic proximity Read