Article
Zinc and its transporters, pancreatic β-cells, and insulin metabolism.
Vitamins and hormones - 1 Jan 2014
Huang Liping
Abstract excerpt
Zinc is an essential trace metal for life. Two families of zinc transporters, SLC30A (ZNT) and SLC39A (ZIP) are required for maintaining cellular zinc homeostasis. ZNTs function to decrease cytoplasmic zinc concentrations whereas ZIPs do the opposite. Expression of zinc transporters can be tissue/cell-type specific or ubiquitous. Zinc transporters that are limited in tissue/cell distributions usually perform...
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