Article

Cytoplasmic zinc regulates IL-1β production by monocytes/macrophages via mTORC1-induced glycolysis in rheumatoid arthritis (RA)

2021-04-17

Abstract excerpt

<h4>ABSTRACT</h4> The essential micronutrient zinc plays regulatory roles in immune responses through its ability to affect signaling pathways. In activated monocytes/macrophages, signaling networks mediate metabolic reprogramming in order to meet the demands of participating in immune responses. Despite its known immunoregulatory roles, the effect of zinc on metabolic reprogramming in monocytes/macrophages remai...

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Literature Corpus work: 9b71d98c-cab5-5d06-97a4-86112099b6b4
DOI: 10.1101/2021.04.16.437150

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