Article

FXR agonism with bile acid mimetic reduces pre-clinical triple-negative breast cancer burden

2024-01-26

Abstract excerpt

Obesity is one of the most prevalent chronic diseases and has become a global epidemic. Obesity leads to a greater risk of breast cancer (BC), metastases, recurrence, and decreased survival. For sustained weight loss, bariatric surgery is effective as a long-term solution. Bariatric surgery is associated with improved outcomes of several cancers including BC, although the mechanisms mediating this protection are u...

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Literature Corpus work: 8370f091-01ef-5b30-9083-a82f1f839179
DOI: 10.20944/preprints202401.1876.v1

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