Article

Heterologous Avian System for Quantitative Analysis of Syncytin-1 Interaction with ASCT2 Receptor

2021-02-24

Abstract excerpt

<title>Abstract</title> <p>BackgroundHuman Syncytin-1 is an envelope glycoprotein of retroviral origin. After interaction with ASCT2, its cellular receptor, Syncytin-1 triggers cell-cell fusion and formation of a multinuclear syncytiotrophoblast layer of the placenta. The ASCT2 receptor is a multi-spanning membrane protein containing a protruding extracellular part called region C, which has been suggested to be...

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Literature Corpus work: 82d76d51-ecca-5c5f-a291-502ff968cdcc
DOI: 10.21203/rs.3.rs-227071/v1

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