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Article

C-Terminal truncations of syncytin-1 (ERVWE1 envelope) that increase its fusogenicity.

Biological chemistry - 1 Aug 2006

Drewlo Sascha, Leyting Simone, Kokozidou Maria, Mallet François, Pötgens Andy J G

Abstract excerpt

Syncytin-1, the envelope protein of ERVWE1, an endogenous retrovirus of the HERV-W family, plays an important role in regulating fusion of the placental trophoblast. At least one of its receptors is expressed on a variety of human cell types. Its ability to fuse cells makes it an attractive candidate molecule in gene therapy against cancer. We studied the relevance of sequences in the cytoplasmic tail of...

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PMID: 16895482
DOI: 10.1515/BC.2006.137

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C-Terminal truncations of syncytin-1 (ERVWE1 envelope) that increase its fusogenicity.PMID 16895482Read ↗

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