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Article

Gene regulatory networks underlying human microglia maturation

2021-06-02

Abstract excerpt

The fetal period is a critical time for brain development, characterized by neurogenesis, neural migration, and synaptogenesis 1-3 . Microglia, the tissue resident macrophages of the brain, are observed as early as the fourth week of gestation 4 and are thought to engage in a variety of processes essential for brain development and homeostasis 5-11 . Conversely, microglia phenotypes are highly regulated by the...

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Literature Corpus work
82c38ad5-2a6f-587e-a184-c90009e6d84a
DOI
10.1101/2021.06.02.446636
Open publication

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Gene regulatory networks underlying human microglia maturationDOI 10.1101/2021.06.02.446636
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