Article

Microglial plasticity governed by state-specific enhancer landscapes

2025-01-31

Abstract excerpt

<h4>SUMMARY</h4> Single-cell transcriptomic studies have identified distinct microglial subpopulations with shared and divergent gene signatures across development, aging and disease. Whether these microglial subsets represent ontogenically separate lineages of cells, or they are manifestations of plastic changes of microglial states downstream of some converging signals is unknown. Furthermore, despite the well-...

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Literature Corpus work: 4828ca5d-1d4f-56dc-a5c5-a9c270a75442
DOI: 10.1101/2025.01.30.635595

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