Article

Epigenetic Reprogramming of Tissue-Specific Transcription Promotes Metastasis

2017-04-26

Abstract excerpt

<h4>SUMMARY</h4> Tumor metastasis is the cause of death for 90% of cancer patients, and no currently-available therapies target this multi-step process in which cancer cells spread from the local tissue of a primary tumor to distant organs where they establish secondary tumors 1 . Although epithelial-to-mesenchymal transition 2 , tumor-secreted exosomes 3 , epigenetic regulators as well as other genes 4-8 hav...

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Literature Corpus work: 82b43d86-3ae6-55de-9d58-84e7ff553df6
DOI: 10.1101/131102

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