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Article

The landscape of T cell epitope immunogenicity in sequence space

2017-06-25

Abstract excerpt

<h4>Summary</h4> The existence of population-wide T cell immunity is widely recognized for multiple pathogen-derived immunodominant epitopes, despite the vast diversity and individualized nature of T cell receptor (TCR) repertoire. We thus hypothesized that population-wide epitope immunogenicity could be probabilistically defined by exploiting public TCR features. To gain a proof-of-concept, here we describe a ma...

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Identifiers and source

Literature Corpus work
82a95b20-d7b0-5e60-b3d2-a817fcde3624
DOI
10.1101/155317
Open publication

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The landscape of T cell epitope immunogenicity in sequence spaceDOI 10.1101/155317
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