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A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responses

2022-10-21

Abstract excerpt

T cell recognition of SARS-CoV-2 antigens after vaccination and/or natural infection has played a central role in resolving SARS-CoV-2 infections and generating adaptive immune memory. However, the clinical impact of SARS-CoV-2-specific T cell responses is variable and the mechanisms underlying T cell interaction with target antigens are not fully understood. This is especially true given the virus’ rapid evolutio...

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Identifiers and source

Literature Corpus work
06375eef-6b2e-58af-9c81-6d813d4f60e9
DOI
10.1101/2022.10.21.513200
Open publication

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A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responsesDOI 10.1101/2022.10.21.513200
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