Article

Cellular and Molecular Probing of Intact Transparent Human Organs

2019-05-21

Abstract excerpt

<h4>SUMMARY</h4> Optical tissue transparency permits cellular and molecular investigation of complex tissues in 3D, a fundamental need in biomedical sciences. Adult human organs are particularly challenging for this approach, owing to the accumulation of dense and sturdy molecules in decades-aged human tissues. Here, we introduce SHANEL method utilizing a new tissue permeabilization approach to clear and label st...

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Literature Corpus work: 49e1d610-1c57-573a-aa02-42b9c30d85e5
DOI: 10.1101/643908

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