Article

The Tumor as a Dynamic Metabolic Interaction Network: From Warburg Effect to Multi-Node Collapse as a Therapeutic Strategy

2026-05-28

Abstract excerpt

Cancer metabolism research has long been shaped by a pathway-centric paradigm, in which individual biochemical routes—most prominently aerobic glycolysis (the Warburg effect)—are studied and targeted in relative isolation. Accumulating evidence from systems biology, multi-omics profiling, and computational oncology suggests, however, that this view is insufficient to explain the adaptive resilience that solid tumo...

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Literature Corpus work: 826a21fa-a386-5d2c-a56e-4e8067029148
DOI: 10.20944/preprints202605.1977.v1

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