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Article

Heterogeneity in Cancer Metabolism: New Concepts in an Old Field.

Antioxidants & redox signaling - 20 Mar 2017

Gentric Géraldine, Mieulet Virginie, Mechta-Grigoriou Fatima

Abstract excerpt

SIGNIFICANCE: In the last years, metabolic reprogramming, fluctuations in bioenergetic fuels, and modulation of oxidative stress became new key hallmarks of tumor development. In cancer, elevated glucose uptake and high glycolytic rate, as a source of adenosine triphosphate, constitute a growth advantage for tumors. This represents the universally known Warburg effect, which gave rise to one major clinical...

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Share to Cell Transformation, Neoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27228792
DOI: 10.1089/ars.2016.6750
PMCID: PMC5359687

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