Article

Microglia contribute to methamphetamine reinforcement and reflect persistent transcriptional and morphological adaptations to the drug

2023-10-23

Abstract excerpt

Methamphetamine use disorder (MUD) is a chronic, relapsing disease that is characterized by repeated drug use despite negative consequences and for which there are currently no FDA-approved cessation therapeutics. Repeated methamphetamine (METH) use induces long-term gene expression changes in brain regions associated with reward processing and drug-seeking behavior, and recent evidence suggests that methamphetami...

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Identifiers and source

Literature Corpus work: 8267866a-89be-5773-af56-acc576e27ccc
DOI: 10.1101/2023.10.19.563168

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