Article

Astrocyte-derived TNF and glutamate critically modulate microglia reactivity by methamphetamine

2021-02-22

Abstract excerpt

Methamphetamine (Meth) is a powerful illicit psychostimulant, widely used for recreational purposes. Besides disrupting the monoaminergic system and promoting oxidative brain damage, Meth also causes neuroinflammation that contributes to synaptic dysfunction and behavioral deficits. Aberrant activation of microglia, the largest myeloid cell population in the brain, is a common feature in neurological disorders lin...

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Literature Corpus work: 64c3f4fe-ada2-531f-a586-d34e350cfc4b
DOI: 10.1101/2021.02.22.432170

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