Article
IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform.
PLoS computational biology - 1 Sept 2014
Hepler N Lance, Scheffler Konrad, Weaver Steven, Murrell Ben, Richman Douglas D, Burton Dennis R, Poignard Pascal, Smith Davey M, Kosakovsky Pond Sergei L
Abstract excerpt
Since its identification in 1983, HIV-1 has been the focus of a research effort unprecedented in scope and difficulty, whose ultimate goals--a cure and a vaccine--remain elusive. One of the fundamental challenges in accomplishing these goals is the tremendous genetic variability of the virus, wit...
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