Article
OxLDL/LOX-1 Mediated Sex, Age, and Cell Dependent Alterations in Mouse Thoracic Aortic Vascular Reactivity
2023-09-10
Abstract excerpt
<h4>ABSTRACT</h4> Elevated oxidized low-density lipoprotein (oxLDL) is a risk factor and component that worsens cardiovascular disease states. OxLDL can elicit its detrimental action, via lectin-like oxLDL receptor 1 (LOX-1) and has been shown to disrupt vascular function. In this study, we determined whether oxLDL, via LOX-1, alters aortic vascular reactivity and determined if sex differences exist. Thoracic aor...
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Identifiers and source
- Literature Corpus work
- 54f5b434-4c91-5992-8c5c-ae22648cfb48
- DOI
- 10.1101/2023.09.07.556764
