Article

Immunophenotyping reveals longitudinal changes in circulating immune cells during radium-223 therapy in patients with metastatic castration-resistant prostate cancer

2020-11-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Radium-223 improves overall survival (OS) in men with bone metastatic castration-resistant prostate cancer (mCRPC). While the exact mechanism behind this survival benefit remains unclear, radium-induced immunological mechanisms might contribute to the OS advantage. We performed a comprehensive evaluation of the immunological changes in mCRPC patients by phenotyping the peripheral...

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Literature Corpus work: 5487d25b-814a-5b15-8e2f-40df44bb2a4a
DOI: 10.1101/2020.11.11.20229831

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