Article

FK506-binding protein 13 expression is upregulated in interstitial lung disease and correlated with clinical severity: a potentially protective role

2019-12-15

Abstract excerpt

<h4>ABSTRACT</h4> Pulmonary fibrosis is a progressive lung disease characterized by myofibroblast accumulation and excessive extracellular matrix deposition. Endoplasmic reticulum (ER) stress initiates the unfolded protein response (UPR), a cellular stress response pathway that has been implicated in both inflammatory and fibrotic processes. Here, we sought to investigate the role of the 13 kDa FK506-binding prot...

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Literature Corpus work: 81c1fc97-ec79-514c-8d77-05ba3f628b82
DOI: 10.1101/2019.12.15.858340

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